MASP1 Antibody - Cat. #: CSB-PA013508LA01HU

SKU: CSB-PA013508LA01HU

Size :50ug

Clone Number:

Aliases:MASP1 antibody; CRARF antibody; CRARF1 antibody; PRSS5Mannan-binding lectin serine protease 1 antibody; EC 3.4.21.- antibody; Complement factor MASP-3 antibody; Complement-activating component of Ra-reactive factor antibody; Mannose-binding lectin-associated serine protease 1 antibody; MASP-1 antibody; Mannose-binding protein-associated serine protease antibody; Ra-reactive factor serine protease p100 antibody; RaRF antibody; Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P48740

Immunogen:Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000

Background:Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MASP1

Research Areas:Immunology