MARH8 Polyclonal Antibody

SKU: BT-AP11124

Size:100μL

Background:MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003

Research_area:Epigenetics and nuclear signaling

Target_protein:MARH8

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:E3 ubiquitin-protein ligase MARCH8

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q5T0T0; Mouse: Q9DBD2

Synonyms:E3 ubiquitin-protein ligase MARCH8 ;EC 6.3.2.-;Cellular modulator of immune recognition;c-MIR;Membrane-associated RING finger protein 8;Membrane-associated RING-CH protein VIII;MARCH-VIII;

GeneID:Human: 220972