MAPK7 Monoclonal Antibody

SKU: BT-MCA2016

Size:100μL

Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Research_area:Others

Target_protein:MAPK7

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:8H1D5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MAPK7

Immunogen:Purified recombinant fragment of human MAPK7 (AA: 411-556) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):88.4kDa

UniProt accession:Q13164

Synonyms:BMK1, ERK4, ERK5, PRKM7

GeneID:5598