MAGEC2 antibody , Cat. # FNab04944

SKU: FNab04944

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes(E2) at the E3:substrate complex.

Immunogen:melanoma antigen family C, 2

Synonyms:Cancer/testis antigen 10, CT10, HCA587, MAGE C2 antigen, MAGE E1 antigen, MAGEC2, MAGEE1, melanoma antigen family C, 2, Melanoma associated antigen C2

Observed MW:41 kDa

Uniprot ID:Q9UBF1

Reactivity:Human

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20 - 1:200

Gene ID:51438

Research Area:Cancer, Developmental biology