MACF1 Antibody, FITC conjugated - Cat. #: CSB-PA890946LC01HU

SKU: CSB-PA890946LC01HU

Size :50ul

Clone Number:

Aliases:MACF1 antibody; ABP620 antibody; ACF7 antibody; KIAA0465 antibody; KIAA1251 antibody; Microtubule-actin cross-linking factor 1 antibody; isoforms 1/2/3/5 antibody; 620 kDa actin-binding protein antibody; ABP620 antibody; Actin cross-linking family protein 7 antibody; Macrophin-1 antibody; Trabeculin-alpha antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UPN3

Immunogen:Recombinant Human Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 protein (1936-2150AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MACF1

Research Areas:Others