LRRC8C antibody , Cat. # FNab04861

SKU: FNab04861

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.

Immunogen:leucine rich repeat containing 8 family, member C

Synonyms:AD158, FAD158

Observed MW:

Uniprot ID:Q8TDW0

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IF, IHC

Recommended dilution:IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:84230

Research Area:Signal Transduction