LRP6 Polyclonal Antibody

SKU: E-AB-17347

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: LRP6

Target Synonym: ADCAD2;C030016K15Rik;Cd;FLJ90062;FLJ90421;LDL receptor related protein 6;Low density lipoprotein receptor related protein 6;Low-density lipoprotein receptor-related protein 6;LRP-6;LRP6;LRP6;OTTHUMP00000238979;OTTHUMP00000238980;OTTHUMP00000238982;STHAG7

Research Areas: Cancer;Signal transduction;Stem cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O75581

Accession:

Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

Concentration: 1.4 mg/mL

Immunogen: Synthetic peptide of human LRP6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:40-200

Calculated MW:

ObservedMW: