LRP5 Monoclonal Antibody

SKU: BT-MCA3804

Size:100μL

Background:This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Research_area:Cardiovascular, Metabolism, Neuroscience , Signal transduction, Stem cells

Target_protein:LRP5

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:2B11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:LRP5

Immunogen:Purified recombinant fragment of human LRP5 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):179kDa

UniProt accession:O75197

Synonyms:HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, OPTA1, VBCH2

GeneID:4041