LRP5 Antibody - Cat. #: CSB-PA255528

SKU: CSB-PA255528

Size :50ul

Clone Number:

Aliases:BMND1 antibody; EVR1 antibody; EVR4 antibody; HBM antibody; Low density lipoprotein receptor related protein 5 antibody; Low density lipoprotein receptor related protein 7 antibody; Low-density lipoprotein receptor-related protein 5 antibody; LR3 antibody; LRP-5 antibody; Lrp5 antibody; LRP5_HUMAN antibody; LRP7 antibody; OPPG antibody; OPS antibody; OPTA1 antibody; Osteoporosis pseudoglioma syndrome antibody; VBCH2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75197

Immunogen:Synthetic peptide of Human LRP5

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:50-1:200

Background:This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LRP5

Research Areas:Neuroscience?Cancer?Cardiovascular;Metabolism;Signal transduction?Stem cells