LOX Antibody - Cat. #: CSB-PA808676

SKU: CSB-PA808676

Size :50ul

Clone Number:

Aliases:lox antibody; LYOX antibody; LYOX_HUMAN antibody; Lysyl oxidase antibody; MGC105112 antibody; Protein lysine 6 oxidase antibody; Protein-lysine 6-oxidase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P28300

Immunogen:Synthetic peptide of Human LOX

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:25-1:100

Background:The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LOX

Research Areas:Cancer?Cardiovascular;Signal transduction