LINGO1 Antibody - Cat. #: CSB-PA839321ESR2HU

SKU: CSB-PA839321ESR2HU

Size :50ul

Clone Number:

Aliases:FLJ14594 antibody; LERN 1 antibody; LERN1 antibody; Leucine rich repeat and Ig domain containing 1 antibody; Leucine rich repeat neuronal 6A antibody; Leucine rich repeat neuronal protein 1 antibody; Leucine rich repeat neuronal protein 6A antibody; Leucine-rich repeat and immunoglobilin domain-containing protein 1 antibody; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 antibody; Leucine-rich repeat neuronal protein 1 antibody; Leucine-rich repeat neuronal protein 6A antibody; LIGO1_HUMAN antibody; Lingo 1 antibody; LINGO1 antibody; LRR and Ig domain containing Nogo Receptor interating protein antibody; Lrrn 6a antibody; Lrrn6a antibody; Lrrn6a protein antibody; MGC17422 antibody; Nogo Receptor interacting protein antibody; PRO227 antibody; UNQ201 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96FE5

Immunogen:Recombinant Human Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 protein (42-240AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LINGO1

Research Areas:Neuroscience; Developmental biology; Signal transduction