LIM and SH3 domain protein 1 rabbit pAb

SKU: ES8817

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized peptide derived from human LIM and SH3 domain protein 1. at AA range: 90-130

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):38kD

Human_gene_id:3927

Human_swiss_prot_no:Q14847

Subcellular_location:Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .

Other_name:LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)

Background:This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],