LILRB1 Monoclonal Antibody

SKU: BT-MCA4569

Size:100μL

Background:This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Research_area:Immunology

Target_protein:LILRB1

applications:FCM

Reactivity:

Clonality:Monoclonal

Clone ID:4B5A4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:LILRB1

Immunogen:Purified recombinant fragment of human LILRB1 (AA: extra 338-461) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):70.8kDa

UniProt accession:Q8NHL6

Synonyms:ILT2, LIR1, MIR7, PIRB, CD85J, ILT-2, LIR-1, MIR-7, PIR-B

GeneID:10859