LGI1 Antibody - Cat. #: CSB-PA012898ESR2HU

SKU: CSB-PA012898ESR2HU

Size :50ul

Clone Number:

Aliases:ADLTE antibody; ADPAEF antibody; ADPEAF antibody; Epitempin 1 antibody; EPITEMPIN antibody; Epitempin-1 antibody; EPT antibody; ETL1 antibody; IB1099 antibody; leucine rich glioma inactivated 1 antibody; Leucine rich glioma-inactivated protein 1 antibody; Leucine-rich glioma-inactivated protein 1 antibody; LGI1 antibody; LGI1_HUMAN antibody; OTTHUMP00000020121 antibody; OTTHUMP00000020122 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95970

Immunogen:Recombinant Human Leucine-rich glioma-inactivated protein 1 protein (35-285AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LGI1

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cancer