LEP Polyclonal Antibody

SKU: E-AB-70170

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:LEP

Target Synonym:FLJ94114;LEP;LEP;LEPD;Leptin (murine obesity homolog);Leptin (obesity homolog;mouse);Leptin;Leptin Murine Obesity Homolog;Leptin Precursor Obesity Factor;OB;Obese protein;Obese;mouse;homolog of;Obesity;Obesity factor;Obesity homolog mouse;Obesity Murine Homolog Leptin;OBS;OTTHUMP00000212285

Research Areas:Cancer;Cardiovascular;Metabolism;Neuroscience;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P41159,P41160,P50596

Accession:

Background:This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Concentration:210 μg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Leptin

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:100

Calculated MW:

ObservedMW: