L1 Antibody, Biotin conjugated - Cat. #: CSB-PA08359D0Rb

SKU: CSB-PA08359D0Rb

Size :50ug

Clone Number:

Aliases:L1 antibody; Major capsid protein L1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human) papillomavirus type 18

UniProt ID:P06794

Immunogen:Recombinant HPV18 Major capsid protein L1 protein (1-568AA)

Raised in:Rabbit

Species Reactivity:Human papillomavirus type 18

Tested Applications:ELISA

Background:Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells. Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:L1

Research Areas:Cancer; Microbiology