KLK7 Antibody - Cat. #: CSB-PA094965

SKU: CSB-PA094965

Size :50ul

Clone Number:

Aliases:Chymotryptic stratum corneum antibody; hK 7 antibody; hK7 antibody; hSCCE antibody; Kallikrein 7 (chymotryptic stratum corneum) antibody; Kallikrein related peptidase 7 antibody; Kallikrein-7 antibody; Kallikrein7 antibody; KLK 7 antibody; Klk7 antibody; KLK7_HUMAN antibody; Protease serine 6 antibody; PRSS 6 antibody; PRSS6 antibody; SCCE antibody; Serine protease 6 antibody; Signal protein antibody; Stratum corneum chymotryptic enzyme antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P49862

Immunogen:Fusion protein of Human KLK7

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100

Background:This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KLK7

Research Areas:Cancer;Cell biology;Signal transduction