GeneBio Systems
KLF12 rabbit pAb
KLF12 rabbit pAb
SKU:ES3849
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Size: 100μL
Source:Rabbit
Applications:WB;IHC;IF;ELISA
Reactivity:Human;Mouse
Dilution:Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen:Synthesized peptide derived from the Internal region of human KLF12.
Storage_stability:-20°C/1 year
Clonality:Polyclonal
Isotype:IgG
Concentration:1 mg/ml
Observed_band(KD):44kD
Human_gene_id:11278
Human_swiss_prot_no:Q9Y4X4
Subcellular_location:Nucleus.
Other_name:KLF12; AP2REP; HSPC122; Krueppel-like factor 12; Transcriptional repressor AP-2rep
Background:Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
