Keap1 Antibody, Biotin conjugated - Cat. #: CSB-PA012147LD01MO

SKU: CSB-PA012147LD01MO

Size :50ug

Clone Number:

Aliases:Keap1 antibody; Inrf2 antibody; Kiaa0132Kelch-like ECH-associated protein 1 antibody; Cytosolic inhibitor of Nrf2 antibody; INrf2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:Q9Z2X8

Immunogen:Recombinant Mouse Kelch-like ECH-associated protein 1 protein (1-624AA)

Raised in:Rabbit

Species Reactivity:Mouse

Tested Applications:ELISA

Background:Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Keap1

Research Areas:Others