KCNK9 (TASK-3) rabbit pAb

SKU: ES20696

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF

Reactivity:Human;Rat;Mouse

Dilution:WB 1:1000-2000, IHC 1:100-200

Immunogen:Synthetic Peptide of KCNK9 (TASK-3) AA range: 220-270

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):42kD

Human_gene_id:51305

Human_swiss_prot_no:Q9NPC2

Subcellular_location:Cell membrane ; Multi-pass membrane protein .

Other_name:Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3;TWIK-related acid-sensitive K(+) channel 3;Two pore potassium channel KT3.2;Two pore K(+) channel KT3.2)

Background:This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],