KAT6B Monoclonal Antibody

SKU: BT-MCA2375

Size:100μL

Background:The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

Research_area:Epigenetics and nuclear signaling

Target_protein:KAT6B

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:8C8D12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:KAT6B

Immunogen:Purified recombinant fragment of human KAT6B (AA: 1186-1318) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):231.4kDa

UniProt accession:Q8WYB5

Synonyms:qkf, MORF, MOZ2, GTPTS, MYST4, ZC2HC6B, querkopf

GeneID:23522