KAT5 Antibody, FITC conjugated - Cat. #: CSB-PA17849C0Rb

SKU: CSB-PA17849C0Rb

Size :50ug

Clone Number:

Aliases:60 kDa Tat interactive protein antibody; 60 kDa Tat-interactive protein antibody; cPLA(2) interacting protein antibody; cPLA(2)-interacting protein antibody; cPLA2 antibody; cPLA2 interacting protein antibody; ESA1 antibody; Histone acetyltransferase HTATIP antibody; Histone acetyltransferase KAT5 antibody; HIV 1 Tat interactive protein antibody; HIV 1 Tat interactive protein, 60kDa antibody; HIV-1 Tat interactive protein antibody; HTATIP antibody; HTATIP1 antibody; K(lysine) acetyltransferase 5 antibody; K-acetyltransferase 5 antibody; KAT5 antibody; KAT5_HUMAN antibody; Lysine acetyltransferase 5 antibody; PLIP antibody; Tat interacting protein, 60kDa antibody; TIP antibody; Tip60 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92993

Immunogen:Recombinant Human Histone acetyltransferase KAT5 protein (3-512AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KAT5

Research Areas:Epigenetics and Nuclear Signaling; Immunology; Microbiology