ITSN1 Antibody - Cat. #: CSB-PA621885LA01HU

SKU: CSB-PA621885LA01HU

Size :50ug

Clone Number:

Aliases:Human intersectin SH3 domain containing protein SH3P17 antibody; Intersectin 1 SH3 domain protein antibody; intersectin 1 short form variant 3 antibody; intersectin 1 short form variant, 11 antibody; Intersectin short form antibody; intersectin short variant 12 antibody; Intersectin-1 antibody; Intersectin1 antibody; ITSN 1 antibody; ITSN antibody; itsn1 antibody; ITSN1_HUMAN antibody; MGC134948 antibody; MGC134949 antibody; OTTHUMP00000067855 antibody; OTTHUMP00000067856 antibody; OTTHUMP00000067857 antibody; OTTHUMP00000194810 antibody; OTTHUMP00000194811 antibody; OTTHUMP00000194812 antibody; OTTHUMP00000206688 antibody; SH3 domain containing protein 1A antibody; SH3 domain protein 1A antibody; SH3 domain-containing protein 1A antibody; SH3D1A antibody; SH3P17 antibody; Src homology 3 domain containing protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15811

Immunogen:Recombinant Human Intersectin-1 protein (773-916AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Background:Acts as guanine nucleotide exchange factor (GEF) specific for the CDC42 GTPase (By similarity). Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ITSN1

Research Areas:Neuroscience; Signal transduction