ITPR2 Polyclonal Antibody

SKU: E-AB-52051

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ITPR2

Target Synonym: 4;5-trisphosphate receptor;Inositol 1 4 5 trisphosphate receptor type 2;Inositol 1;4;5-trisphosphate receptor type 2;Inositol 145 trisphosphate receptor type 2;InsP3 R2;InsP3R2;IP3 R2;IP3 receptor;IP3 receptor isoform 2;IP3R 2;IP3R2;ITPR 2;Itpr2;ITPR2;Type 2 inositol 1 4 5 trisphosphate receptor;Type 2 inositol 1;Type 2 inositol 145 trisphosphate receptor;Type 2 InsP3 receptor

Research Areas: Cancer;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q14571

Accession:

Background: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.

Concentration: 1.74 mg/mL

Immunogen: Synthetic peptide of human ITPR2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:300

Calculated MW:

ObservedMW: