IRS-1 (phospho-Ser318) rabbit pAb

SKU: ES15425

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Mouse

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:Synthesized phosho peptide around human IRS-1 (Ser318)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):170kD

Human_gene_id:3667

Human_swiss_prot_no:P35568

Subcellular_location:nucleus,cytoplasm,cytosol,plasma membrane,insulin receptor complex,caveola,intracellular membrane-bounded organelle,

Other_name:Insulin receptor substrate 1 (IRS-1)

Background:This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],