IREB2 Antibody - Cat. #: CSB-PA011813LA01HU

SKU: CSB-PA011813LA01HU

Size :50ug

Clone Number:

Aliases:ACO3 antibody; FLJ23381 antibody; IRE BP2 antibody; IRE-BP 2 antibody; IREB 2 antibody; IREB2 antibody; IREB2_HUMAN antibody; Iron regulatory protein 2 antibody; iron responsive element binding protein 2 antibody; Iron-responsive element-binding protein 2 antibody; IRP 2 antibody; IRP2 antibody; IRP2AD antibody; OTTHUMP00000185022 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P48200

Immunogen:Recombinant Human Iron-responsive element-binding protein 2 protein (107-216AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5\\\'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3\\\'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IREB2

Research Areas:Cardiovascular; Metabolism