IPO7 Antibody - Cat. #: CSB-PA589740

SKU: CSB-PA589740

Size :50ul

Clone Number:

Aliases:FLJ14581 antibody; Imp 7 antibody; Imp7 antibody; Importin-7 antibody; Importin7 antibody; IPO 7 antibody; IPO7 antibody; IPO7_HUMAN antibody; MGC138673 antibody; Ran binding protein 7 antibody; Ran-binding protein 7 antibody; RANBP 7 antibody; RanBP7 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95373

Immunogen:Synthetic peptide of Human IPO7

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300

Background:The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IPO7

Research Areas:Epigenetics and Nuclear Signaling;Signal transduction