IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody

SKU: BT-AP10616

Size:100μL

Background:This gene encodes an intracellular receptor for inositol 1|4|5-trisphosphate. Upon stimulation by inositol 1|4|5-trisphosphate| this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15| a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Research_area:Cancer; Metabolism; Signal transduction; Neuroscience

Target_protein:ITPR1

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:IP3 Receptor

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):303380

UniProt accession:Human: Q14643; Mouse: P11881; Rat: P29994

Synonyms:IP3 Receptor ;Phospho Tyr353; Inositol 1; 4; 5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1; 4; 5-trisphosphate receptor; Type 1 InsP3 receptor

GeneID:Human: 3708; Mouse: 16438; Rat: 25262