InVivoMAb Anti-Rat CD198/CCR8 Antibody (Iv0256)

SKU: RW444010

Size:100ug

Description:CCR8, a receptor selectively expressed on activated Tregs within tumors, plays a key role in maintaining local immunosuppression. Iv0256 is a rat-reactive CCR8 antibody with improved functional potency. In CD34 humanized mice, Iv0256 markedly reduced HCC827 lung tumor growth after intravenous administration. In syngeneic LLC and H22 models, intraperitoneal Iv0256 also achieved robust tumor suppression, displaying a pronounced dose-response pattern across tested doses.

Host species:Mouse

Species reactivity:Rat

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG2a, kappa

Applications:ELISA, Neutralization

Target:C-C motif chemokine receptor 8, Ccr8

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Accession:D4ADE0

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID:Iv0256

Product Usage Information:

Predicted molecular weight:

Note:For research use only. Not suitable for clinical or therapeutic use.