INTS6 Antibody, Biotin conjugated - Cat. #: CSB-PA011764LD01HU

SKU: CSB-PA011764LD01HU

Size :50ug

Clone Number:

Aliases:DBI 1 antibody; DBI-1 antibody; DBI1 antibody; DDX26 antibody; DDX26A antibody; DEAD box protein antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26 antibody; Deleted in cancer 1 antibody; DICE1 antibody; DKFZp434B105 antibody; HDB antibody; Int6 antibody; INT6_HUMAN antibody; Integrator complex subunit 6 antibody; INTS 6 antibody; ints6 antibody; Notchl2 antibody; OTTHUMP00000018439 antibody; OTTHUMP00000215034 antibody; OTTHUMP00000215036 antibody; Protein DDX26 antibody; Protein deleted in cancer 1 antibody; RNA helicase HDB antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UL03

Immunogen:Recombinant Human Integrator complex subunit 6 protein (571-795AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3\'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:INTS6

Research Areas:Epigenetics and Nuclear Signaling; Cancer