INS Antibody - Cat. #: CSB-PA285156

SKU: CSB-PA285156

Size :50ul

Clone Number:

Aliases:IDDM 2 antibody; IDDM2 antibody; ILPR antibody; ins antibody; INS_HUMAN antibody; Insulin A chain antibody; IRDN antibody; MODY10 antibody; Proinsulin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P01308

Immunogen:Synthetic peptide of Human INS

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:INS

Research Areas:Neuroscience?Cancer?Cardiovascular;Metabolism;Signal transduction