IMPDH2 Polyclonal Antibody

SKU: E-AB-11330

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:IMPDH2

Target Synonym:IMDH2;IMP (inosine monophosphate) dehydrogenase 2;IMP dehydrogenase 2;IMP oxireductase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH II;IMPDH-II;Impdh2;Inosine 5' monophosphate dehydrogenase 2;Inosine 5' phosphate dehydrogenase 2;Inosine monophosphate dehydrogenase type II;Inosine-5''-monophosphate dehydrogenase 2

Research Areas:Cancer;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P12268

Accession:

Background:This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Concentration:0.5 mg/mL

Immunogen:Recombinant protein of human IMPDH2

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:56kDa

ObservedMW: