IL17RC Antibody - Cat. #: CSB-PA185992

SKU: CSB-PA185992

Size :100ul

Clone Number:

Aliases:IL17RC antibody; UNQ6118/PRO20040/PRO38901Interleukin-17 receptor C antibody; IL-17 receptor C antibody; IL-17RC antibody; Interleukin-17 receptor homolog antibody; IL17Rhom antibody; Interleukin-17 receptor-like protein antibody; IL-17RL antibody; ZcytoR14 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8NAC3

Immunogen:Synthesized peptide derived from internal of Human IL17RC.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

Gray A.M., Genome Res. 13:2265-2270(2003).
Gibbs R.A., Nature 440:1194-1198(2006).
Henzel W.J., Protein Sci. 13:2819-2824(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IL17RC

Research Areas:Immunology