IL-1F6 rabbit pAb

SKU: ES8729

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:IHC-p 1:50-200, ELISA 1:10000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human IL36A. AA range:21-70

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:27179

Human_swiss_prot_no:Q9UHA7

Subcellular_location:Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .

Other_name:Interleukin-36 alpha (FIL1 epsilon;Interleukin-1 epsilon;IL-1 epsilon;Interleukin-1 family member 6;IL-1F6)

Background:The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015],