IGF2BP3 Antibody, HRP conjugated - Cat. #: CSB-PA011092LB01HU

SKU: CSB-PA011092LB01HU

Size :50ug

Clone Number:

Aliases:Cancer/testis antigen 98 antibody; CT98 antibody; DKFZp686F1078 antibody; hKOC antibody; IF2B3_HUMAN antibody; IGF II mRNA binding protein 3 antibody; IGF-II mRNA-binding protein 3 antibody; IGF2 mRNA binding protein 3 antibody; IGF2 mRNA-binding protein 3 antibody; IGF2BP3 antibody; IMP 3 antibody; IMP-3 antibody; Insulin like growth factor 2 mRNA binding protein 3 antibody; Insulin-like growth factor 2 mRNA-binding protein 3 antibody; KH domain containing protein overexpressed in cancer antibody; KH domain-containing protein overexpressed in cancer antibody; KOC 1 antibody; KOC1 antibody; VICKZ 3 antibody; VICKZ family member 3 antibody; VICKZ3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O00425

Immunogen:Recombinant Human Insulin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \'caging\' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5\'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IGF2BP3

Research Areas:Epigenetics and Nuclear Signaling; Cancer