IGF2 Polyclonal Antibody

SKU: BT-AP08851

Size:100μL

Background:This gene encodes a member of the insulin family of polypeptide growth factors| which are involved in development and growth. It is an imprinted gene| expressed only from the paternal allele| and epigenetic changes at this locus are associated with Wilms tumour| Beckwith-Wiedemann syndrome| rhabdomyosarcoma| and Silver-Russell syndrome. A read-through INS-IGF2 gene exists| whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area: Signal transduction; Cancer; Developmental biology; Stem cells

Target_protein:IGF2

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Insulin-like growth factor II

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P01344; Mouse: P09535; Rat: P01346

Synonyms:Insulin-like growth factor II (IGF-II;Somatomedin-A) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin]

GeneID:Human: 3481