IFIT2 Antibody, FITC conjugated - Cat. #: CSB-PA011021LC01HU

SKU: CSB-PA011021LC01HU

Size :50ug

Clone Number:

Aliases:CIG-42 antibody; cig42 antibody; G10P2 antibody; GARG 39 antibody; Glucocorticoid attenuated response gene 39 antibody; IFI 54 antibody; IFI 54K antibody; IFI-54K antibody; IFI54 antibody; IFIT 2 antibody; IFIT-2 antibody; IFIT2 antibody; IFIT2_HUMAN antibody; Interferon induced 54 kDa protein antibody; Interferon induced protein 54 antibody; Interferon induced protein with tetratricopeptide repeats 2 antibody; Interferon, alpha inducible protein (MW 54kD) antibody; Interferon-induced 54 kDa protein antibody; Interferon-induced protein with tetratricopeptide repeats 2 antibody; ISG 54 K antibody; ISG 54K antibody; ISG-54 K antibody; ISG54 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P09913

Immunogen:Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2 protein (130-265AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2\'-O-methylation of the 5\' cap. The ribose 2\'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2\'-O-methylase for their mRNAs or by stealing host cap containing the 2\'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5\' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IFIT2

Research Areas:Immunology; Signal transduction