IDH3B Antibody - Cat. #: CSB-PA114986

SKU: CSB-PA114986

Size :50ul

Clone Number:

Aliases:FLJ11043 antibody; H-IDHB antibody; Idh3B antibody; IDH3B_HUMAN antibody; Isocitrate dehydrogenase [NAD] subunit beta antibody; Isocitrate dehydrogenase [NAD] subunit beta; mitochondrial antibody; isocitrate dehydrogenase 3; beta subunit antibody; Isocitric dehydrogenase antibody; Isocitric dehydrogenase subunit beta antibody; MGC903 antibody; mitochondrial antibody; NAD(+)-specific ICDH antibody; NAD(+)-specific ICDH subunit beta antibody; NAD+-specific isocitrate dehydrogenase b subunit antibody; NAD+-specific isocitrate dehydrogenase beta antibody; OTTHUMP00000030023 antibody; OTTHUMP00000030024 antibody; RP46 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43837

Immunogen:Fusion protein of Human IDH3B

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

Background:Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IDH3B

Research Areas:Cancer;Metabolism;Signal transduction