IAPP Antibody - Cat. #: CSB-PA949254

SKU: CSB-PA949254

Size :50ul

Clone Number:

Aliases:Amylin antibody; DAP antibody; Diabetes associated peptide antibody; Diabetes-associated peptide antibody; IAP antibody; IAPP antibody; IAPP_HUMAN antibody; Insulinoma amyloid peptide antibody; Islet amyloid polypeptide (diabetes associated peptide, amylin) antibody; Islet amyloid polypeptide antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P10997

Immunogen:Synthetic peptide of Human IAPP

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IAPP

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction