Human Voltage Gated Potassium Channel Subunit Beta-2, KCNAB2 ELISA Kit

SKU: E1757Hu

Size:96 Tests-1 Kit

Background:Cytoplasmic potassium Channel subunit that modulates the characteristics of the Channel-forming alpha-subunits (PubMed: 7649300, PubMed: 11825900). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases Channel activity (By similarity). Promotes potassium Channel closure via a mechanism that does not involve physical obstruction of the Channel pore (PubMed: 7649300, PubMed: 11825900). Promotes KCNA4 Channel closure (PubMed: 7649300, PubMed: 11825900). Modulates the functional properties of KCNA5 (By similarity). Enhances KCNB2 Channel activity (By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity (By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:KCNAB2

Reactivity:Human

Assay type:Sandwich

Sensitivity:13.15ng/L

Detection range:20-7000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Voltage Gated Potassium Channel Subunit Beta-2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13303

MASS(Da):41,000

GeneID:8514

Synonyms:hKvbeta2;K(+ Channel subunit beta-2;KCNAB 2;KCNAB2;Kv-beta-2;Voltage-gated potassium Channel subunit beta-2

Gene names:KCNAB2

Standard solution:8000ng/L