Human Vasohibin-1,VASH1 ELISA KIT

SKU: E6395Hu

Size:96 Tests-1 Kit

Background:Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:29146869, PubMed:31270470, PubMed:31235910, PubMed:31171830, PubMed:31235911). Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning (PubMed:31171830). Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis (PubMed:15467828, PubMed:16488400, PubMed:16707096, PubMed:19204325). This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts (PubMed:15467828, PubMed:16488400, PubMed:16707096). {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:16488400, ECO:0000269|PubMed:16707096, ECO:0000269|PubMed:19204325, ECO:0000269|PubMed:29146869, ECO:0000269|PubMed:31171830, ECO:0000269|PubMed:31235910, ECO:0000269|PubMed:31235911, ECO:0000269|PubMed:31270470}.

Research_area:

Applications:ELISA

Target_protein:VASH1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.25ng/L

Detection range:20-7000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Vasohibin-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q7L8A9

MASS(Da):40957

GeneID:22846

Synonyms:VASH1 KIAA1036 VASH

Gene names:VASH1

Standard solution:8000ng/L