Human Vascular Endothelial Cell Growth Factor A, VEGF-A ELISA Kit

SKU: E0050Hu

Size:96 Tests-1 Kit

Background:Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).

Research_area:Cancer

Applications:ELISA

Target_protein:VEGFA

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.52ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Vascular Endothelial Cell Growth Factor A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P15692

MASS(Da):27,042

GeneID:7422

Synonyms:Vascular endothelial growth factor A;Vascular permeability factor;VEGF A;VEGFA;VEGF-A;VPF

Gene names:VEGFA

Standard solution:960ng/L