Human V-type proton ATPase 116 kDa subunit a isoform 2,ATP6V0A2 ELISA KIT

SKU: E6404Hu

Size:96 Tests-1 Kit

Background:Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). {ECO:0000269|PubMed:16415858, ECO:0000269|PubMed:18157129, ECO:0000269|PubMed:28296633}.

Research_area:

Applications:ELISA

Target_protein:ATP6V0A2

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.13ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:V-type proton ATPase 116 kDa subunit a isoform 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y487

MASS(Da):98082

GeneID:23545

Synonyms:ATP6V0A2

Gene names:ATP6V0A2

Standard solution:4800ng/L