Human Ubiquitin-fold modifier 1,UFM1 ELISA KIT

SKU: E7102Hu

Size:96 Tests-1 Kit

Background:Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847, PubMed:29868776, PubMed:27653677). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847, PubMed:29868776, PubMed:27653677). Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (PubMed:32160526). Ufmylation of TRIP4 regulates nuclear receptors-mediated transcription (PubMed:25219498). {ECO:0000269|PubMed:15071506, ECO:0000269|PubMed:20018847, ECO:0000269|PubMed:25219498, ECO:0000269|PubMed:27653677, ECO:0000269|PubMed:29868776, ECO:0000269|PubMed:32160526}.

Research_area:

Applications:ELISA

Target_protein:UFM1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.08ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P61960

MASS(Da):9118

GeneID:51569

Synonyms:UFM1 C13orf20 BM-002

Gene names:UFM1

Standard solution:24ng/ml