Human TRKC ELISA Kit PicoKine®

SKU: EK1676

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: NTRK3

Specificity: Natural and recombinant human TRKC

Background: Tropomyosin receptor kinase C? (TrkC),?also known as?NT-3 growth factor receptor,?neurotrophic tyrosine kinase receptor type 3, or?TrkC tyrosine kinase?is a?protein?that in humans is encoded by the?NTRK3?gene.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.?

Immunogen: Expression system for standard: NS0; Immunogen sequence: C32-A428

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Reference:

Uniprot ID: Q16288

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4916

Protein Name: NT-3 growth factor receptor

Gene Full Name: neurotrophic receptor tyrosine kinase 3

Synonyms: GP145 TrkC; gp145(trkC); NT 3 growth factor receptor; NTRK3; TrkC; TrkC tyrosine kinase