Human Total DDR2 ELISA Kit PicoKine®

SKU: EK2384

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: DDR2

Specificity: Natural and recombinant human total DDR2

Background: Discoidin domain-containing receptor 2, also known as CD167b (cluster of differentiation 167b), is a protein that in humans is encoded by the DDR2 gene. This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia.

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Reference:

Uniprot ID: Q16832

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4921

Protein Name: Discoidin domain-containing receptor 2

Gene Full Name: discoidin domain receptor tyrosine kinase 2

Synonyms: DDR2; Discoidin domain receptor 2; MIG20a; NTRKR3; TKT; TYRO10; Tyrosine protein kinase TYRO10