Human TNFRSF18/GITR ELISA Kit PicoKine®

SKU: EK0768

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TNFRSF18

Specificity: Natural and recombinant human TNFRSF18

Background: Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. This gene is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q26-E161

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: Q9Y5U5

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 8784

Protein Name: Tumor necrosis factor receptor superfamily member 18

Gene Full Name: TNF receptor superfamily member 18

Synonyms: TNF receptor superfamily member 18; AITR; CD357; ENERGEN; GITR; GITR-D; TNFRSF18