Human TNFRSF14/HVEM PicoKine® Quick ELISA Kit

SKU: FEK1226

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TNFRSF14

Specificity: Natural and recombinant human TNFRSF14

Background: Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), also known as HVEM, is a protein that in humans is encoded by the TNFRSF14 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. It is mapped to 1p36.32. HVEM plays an important role in HSV pathogenesis because it enhanced the entry of several wildtype HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T cells. HVEM and BTLA which are form a biional signaling pathway can regulate cell survival and inhibitory responses between interacting cells. HVEM as an important orchestrator of mucosal immunity integrates signals from innate lymphocytes to induce optimal epithelial Stat3 activation, which indicated that targeting HVEM with agonists could improve host defense.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L39-V202

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Uniprot ID: Q92956

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 8764

Protein Name: Tumor necrosis factor receptor superfamily member 14

Gene Full Name: TNF receptor superfamily member 14

Synonyms: ATAR; Herpes virus entry mediator A; Herpesvirus entry mediator A; HVEA; HVEM; LIGHTR; TNFRSF14; TR2