Human Synaptotagmin 1,SYT1 ELISA KIT

SKU: E6980Hu

Size:96 Tests-1 Kit

Background:Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003). {ECO:0000250|UniProtKB:P46096, ECO:0000269|PubMed:23999003}.

Research_area:

Applications:ELISA

Target_protein:SYT1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.2ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Synaptotagmin 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P21579

MASS(Da):47573

GeneID:6857

Synonyms:SYT1 SVP65 SYT

Gene names:SYT1

Standard solution:48ng/ml