Human Stanniocalcin-2, STC2 ELISA Kit

SKU: E6221Hu

Size:96 Tests-1 Kit

Background:Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Research_area:Others

Applications:ELISA

Target_protein:STC2

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.28ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Stanniocalcin-2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O76061

MASS(Da):33,249

GeneID:8614

Synonyms:Stanniocalcin-2;Stanniocalcin-related protein;STC2;STC-2;STC-related protein;STCRP

Gene names:STC2

Standard solution:4800ng/L